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Studies & Results

CIRG/TORI 010

A Randomized Phase 2 Trial of Double-Blind, Placebo Controlled AMG 706 in Combination with Paclitaxel, or Open-Label Bevacizumab in Combination with Paclitaxel, as First Line Therapy in Women with HER2 Negative Locally Recurrent or Metastatic Breast Cancer

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Presentations

San Antonio Breast Cancer Symposium, 2009

Mackey J, Hurvitz S, Crown J, et al

CIRG/TORI 010: 10-Month Analysis of a Randomized Phase II Trial of Motesanib Plus Weekly Paclitaxel as First Line Therapy in HER2-Negative Metastatic Breast Cancer.

ESMO/ECCO Congress, 2009

Martin M, Hurvitz S, Kennedy J, et al

10-months analysis of a randomized, placebo controlled, phase II trial of motesanib plus weekly paclitaxel as first line therapy in HER2 - negative metastatic breast cancer.

Publications

Martin M, Roche H, Pinter T, et al: Motesanib, or open-label bevacizumab, in combination with paclitaxel, as first-line treatment for HER2-negative locally recurrent or metastatic breast cancer: a phase 2, randomised, double-blind, placebo-controlled study. Lancet Oncol 12:369–376, 2011

For information on any of TRIO's clinical trials, please contact Valérie Bee, Director Project Management at valerie.bee@trioncology.org